Beyond amyloid plaques: AI reveals hidden chemical changes across the Alzheimer’s brain

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Scientists at Rice University have produced the first full, dye-free molecular atlas of an Alzheimer’s brain. By combining laser-based imaging with machine learning, they uncovered chemical changes that spread unevenly across the brain and extend beyond amyloid plaques. Key memory regions showed major shifts in cholesterol and energy-related molecules. The findings hint that Alzheimer’s is a whole-brain metabolic disruption—not just a protein problem.

Source: https://www.sciencedaily.com/releases/2 ... 093505.htm
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